Paul Saladino, MD explains how we may have overstated the health benefits of plants and who can benefit from going nose-to-tail carnivore.
02:30 If you eat an animal, nose to tail, you will get everything you need to function optimally.
04:30 Plants don’t want to be eaten and have developed antinutrients to dissuade insects and animals from eating them in abundance.
05:35 About 2 ½ million years ago in our evolution, there was a shift in our primate lineage when we began eating animals far more than plants.
08:03 Eating plants is not optimal or ideal.
09:11 Fossil records of Neanderthals and homo sapiens from northern Europe show that they were high level carnivores, higher than other known animal carnivores.
11:51 It is difficult to look at existing hunter gatherers and make conclusions about where we came from. 16:37 Perhaps our view of polyphenols and fiber are incorrect.
19:51 Most polyphenols and plant compounds are plant defense chemicals called phytoalexins. These compounds are to defend the plant against insects and fungus.
23:19 Why do we think plant compounds/plant defense chemicals are good for us? In research we assume that they have benefit.
30:43 The concept of molecular hormesis is not the same as environmental hormesis. We should look at these compounds for their overall impact, not just the beneficial aspects.
34:57 It difficult to outsmart 3 million years of natural history and evolution.
37:11 Vegan diets are full of plant toxins.
38:04 What is in your supplements?
40:25 The estrogens are in high levels in American grain fed cattle and almost none in Japanese cattle.
41:18 Mycoestrogen is a mold pellet that is placed in a cow’s ear so the cow will need 30% less feed/get 30% fatter on the same amount of feed.
50:50 Organ meats are cheap, cheaper than muscle meat.
51:17 Food is the arbiter of the quality of your life. Functional nutrition and root cause nutrition is not part of western medical training.
55:57 Two meals a day is common with a carnivore diet.
58:27 Eating only muscle meat is not nutritionally complete.
58:57 Protein consumption in humans has a sweet spot and is probably individual to each human..
59:30 Your body does not run on protein. Humans run on either fat or carbohydrate. We use protein as building blocks.
01:01:01 A fasting glucose of 70 to 80 is the sweet spot.
01:01:45 The sweet spot for protein may be about .6 to 1.1 grams per pound of lean body weight. Eat more fat.
01:02:34 Valuable glucose information is garnered with an A.M. glucose test, before you eat and 45 min to 1 hour post-prandial.
01:06:38 If you are in ketosis, LDL generally rises.
01:09:22 When you are on a fat-based metabolism and making ketones, your body makes more cholesterol. Ketones and cholesterol share a common pathway in the liver.
01:17:34 Dr. Saladino has found that patients on carnivore or keto are more hormonally sensitive. T3 decreases with tissue sensitivity and antibodies come down.
01:21:01 Most flavonoids have estrogenic activity, stimulating the estrogen receptor.
01:23:51 There are no reports of vitamin A toxicity from overconsumption of beef or lamb liver. Vitamin A in food form is processed differently than from a supplement.
01:24:45 Choline is in liver, egg yolks and muscle meat. It can turn into TMAO. It is a precursor for phosphatidyl choline, needed to make membranes in our cells. It is a precursor for acetylcholine.
01:25:57 Riboflavin: People are probably not getting enough riboflavin. This is probably behind the activation of different MTHFR polymorphisms.